论文部分内容阅读
糖尿病微血管病变的发病机理尚不明瞭。一般认为除了血管方面的因素外,血液流变学的异常可能会影响微血管内血流.血浆和全血粘度增加、红细胞聚集性及红细胞脆性的增加,均可以导致血液流变学的异常,这些改变对糖尿病微血管病变的发生可能有一定影响。 病人和方法:糖尿病59人。Ⅰ型22人,平均年龄29岁,平均病程12年;Ⅱ型37人,17人用胰岛素治疗,平均年龄60岁,平均病程12年;20人用饮食及口服降糖药治疗,平均年龄55岁,平均病程14年。所有病人均行详细眼科检查,包括眼底照相和荧光血管造影,并根据结果分为无视网膜病变,后部视网膜病变和增殖性视网膜病变三级。对照组57人,平均年龄52岁。
The pathogenesis of diabetic microangiopathy is unclear. It is generally believed that in addition to the vascular factors, abnormalities in hemorheology may affect microvascular blood flow, which may lead to abnormalities in hemorheology as a result of increased plasma and whole blood viscosity, increased erythrocyte aggregation, and increased erythrocyte fragility Changes in the occurrence of diabetic microangiopathy may have some impact. Patients and Methods: Diabetes 59 people. Type I 22 patients, mean age 29 years, with an average duration of 12 years; Type II 37 people, 17 were treated with insulin, mean age 60 years, the average duration of 12 years; 20 were treated with diet and oral hypoglycemic agents, mean age 55 Years old, the average duration of 14 years. All patients underwent detailed eye examination, including fundus photography and fluorescein angiography, and according to the results were divided into no retinopathy, posterior retinopathy and proliferative retinopathy three. The control group of 57 people, average age 52 years old.