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目的：检测阴茎癌患者腹股沟肿大淋巴结中ras癌基因产物严P(21)蛋白的表达状况。方法：采用ABC免疫组化技术。结果：P(21)蛋白在癌性、炎性淋巴结表达阳性者，均表现了平均半年内局部复发和17个月时骨盆淋巴结转移的不良预后。结论：说明P(21)蛋白检测可以作为阴茎癌术后复发、转移和预后效果判定的客观指标之一。
Objective: To detect the expression of ras oncogene P (21) protein in inguinal lymph nodes in patients with penile cancer. Methods: ABC immunohistochemical technique was used. Results: The positive expression of P (21) protein in cancerous and inflammatory lymph nodes all showed an average prognosis of local recurrence within 6 months and pelvic lymph node metastasis at 17 months. Conclusion: The detection of P (21) protein can be used as one of the objective indicators of postoperative recurrence, metastasis and prognosis of penile cancer.