对于继发性口服降糖药无效的非胰岛素依赖性糖尿病(NIDDM)患者采用胰岛素时,一般为每日1次注射中效胰岛素,因此法能够使血糖一日变动接近正常范围。然而,NIDDM 患者虽能大致维持24小时胰岛素的基础分泌,但对餐后血糖的迅速上升却不能出现追加分泌。本文主要研究对 NIDDM 通过餐前注射短效胰岛素,来代替餐后胰岛素的追加分泌。病人和方法 15例患者,男7、女8例,年龄 For patients with non-insulin-dependent diabetes mellitus (NIDDM) who are ineffective in secondary oral hypoglycemic agents, insulin is administered in a single daily dose of 1 hour, so that the daily blood glucose changes can approximate the normal range. However, although patients with NIDDM generally maintain 24-hour basal insulin secretion, there is no additional secretion of post-prandial glucose. This article focuses on the NIDDM by short-acting insulin injection before meals to replace the postprandial insulin secretion. Patients and methods 15 patients, 7 males and 8 females, age