绝大多数幽门螺杆菌(Hp)感染发生在儿童期,罕有自发清除。Hp感染可改变胃肠道原有微生态,导致疾病发生和发展。近年来,Hp耐药性增加等因素使经典的三联疗法治愈率下降。微生态疗法被用于防治Hp感染,可抑制Hp活性和降低药物副反应,具有较好的应用前景。 The vast majority of Helicobacter pylori (Hp) infections occur in childhood, with rare spontaneous clearance. Hp infection can change the original gastrointestinal micro-ecology, leading to the occurrence and development of the disease. In recent years, Hp resistance and other factors make the cure rate of classical triple therapy decreased. Microecological therapy is used to prevent Hp infection, inhibit Hp activity and reduce side effects of drugs, has a good prospect.