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胸腺切除已被公认为治疗重症肌无力(MG)的一种方法,但术后不久会发生MG危象,有增加近期死亡的危险。本院收治4例结合治疗体会进行讨论。临床资料见下表: 讨论一、发生危象的原因:多数学者认为本病病变部位在胸腺,患者胸腺内有异常的横纹肌样细胞,它可作为抗原而使血中产生相应的抗体,这种抗体可刺激胸腺上皮细胞,使之分泌过多的胸腺素,因而抑制神末梢乙酰胆硷的合成,从而产生MG症状。根据这一理论有人提出对难治型MG
Thyroidectomy has been recognized as a method for the treatment of myasthenia gravis (MG), but MG crisis will occur soon after surgery, increasing the risk of recent death. 4 cases of combined treatment in our hospital were discussed. The clinical data is shown in the following table: Discussion I. Causes of crisis: Most scholars believe that the disease is located in the thymus gland and there are abnormal rhabdoid cells in the patient’s thymus. It can be used as an antigen to produce antibodies in the blood. Antibodies stimulate thymic epithelial cells to secrete excessive amounts of thymosin, thus inhibiting the synthesis of acetylcholine in the distal part of the god, thereby producing MG symptoms. According to this theory, it was proposed to refractory MG