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白血病抑制因子(LIF)是细胞因子中的一种,它能抑制胚胎性干细胞的分化,又能诱导 M1白血病细胞的分化。本文对 LIF 的生物学作用及其 LIF 受体的生物化学和生物学特性作一介绍。
Leukemia inhibitory factor (LIF) is one of cytokines, it can inhibit the differentiation of embryonic stem cells, but also induce the differentiation of M1 leukemia cells. This article describes the biological role of LIF and its biochemical and biological properties of LIF receptor.