青霉素是临床上应用最多的抗菌药,其过敏反应可致严重休克。但临床上青霉素肌注引起昏厥多数并非由于过敏所致,也不能由皮肤试验所预测。因临床上发生率较高,其表现症状与青霉素过敏休克颇相类似,容易造成误诊,使病人失去应用一种有效药物的机会,值得注意加以区别。凡出现这种昏厥的,继续使用青毒素并非禁忌。本文报告根据广西田林县农忠鲁、赵爱芳医师观察收集的青霉素注射反应病例10名及提出的问题,我院儿科、耳鼻喉科、内科、皮肤科、病理生理教研组有关同志进行了专题讨论,研究了鉴别诊断和发病机制,并提出相应的防治措施。农医师等提出的问题是带有一定的普遍意义的,他们的材料如下: Penicillin is the most widely used antibacterial drug in clinical practice, its allergic reaction can cause severe shock. However, most clinical intracranial penicillin caused by syncope is not due to allergies, nor can it be predicted by the skin test. Due to the high incidence of clinical manifestations of symptoms similar to penicillin shock similar to easily lead to misdiagnosis, the patient lost the opportunity to apply an effective drug, it is worth noting to be distinguished. Where there is such a fainting, the continued use of green toxins is not a taboo. In this paper, according to 10 cases of penicillin injection reactions and the problems raised by the physicians of Nongzhong Lu and Zhao Aifang in Tianlin County, Guangxi Province, the relevant comrades in Pediatrics, Otorhinolaryngology, Internal Medicine, Dermatology and Pathophysiology of our hospital were discussed in a special topic. The differential diagnosis and pathogenesis, and put forward the corresponding prevention and treatment measures. The questions put forward by the farmers, etc., are of some universal significance. Their material is as follows: