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在抗氯喹恶性疟疾地区用青蒿素及其衍生物——蒿甲醚和还原青蒿素琥珀酸单酯钠治疗脑型疟140例,并配合对症处理和积极防治并发症等治疗措施,治愈128例,死亡12例,治愈率91.4％,病死率8.6％。临床试用表明,这些药物杀虫速度较氯喹、奎宁快,无毒性反应,使用简便安全,可作为治疗危重疟疾患者的首选药物。
140 cases of cerebral malaria were treated with artemisinin and its derivatives artemether and artemisinin succinate monoester sodium in the anti-chloroquine-resistant malaria area and treated with symptomatic treatment and active prevention and treatment of complications and other treatment measures 128 cases, 12 deaths, the cure rate was 91.4% and the case fatality rate was 8.6%. Clinical trials show that these drugs are faster than chloroquine, quinine, non-toxic reactions, easy to use and safe, can be used as the treatment of critically ill patients with malaria drugs.