论文部分内容阅读
[目的]观察滋肾固精凉血方联合西药治疗早期糖尿病肾病疗效。[方法]使用随机平行对照方法,将84例住院患者按抛硬币方法随机分为两组。对照组42例西医基础治疗。治疗组42例滋肾固精凉血方(桑葚子、仙灵脾各12g,枸杞子、女贞子、复盆子、旱莲草、白芍各15g,熟首乌、菟丝子、丹皮各20g),1剂/d,水煎1000mL,早晚两次服用。西药治疗同对照组。连续治疗60d为1疗程。观测临床症状、生化指标(血糖、餐后2h血糖、糖化血红蛋白、血清肌酐、尿蛋白排泄率)、不良反应。连续治疗1疗程,判定疗效。[结果]治疗组显效17例,有效19例,无效6例,总有效率85.70%。对照组显效10例,有效16例,无效16例,总有效率61.90%。治疗组疗效优于对照组(P<0.05)。血糖、餐后2h血糖、糖化血红蛋白、血清肌酐、尿蛋白排泄率两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]滋肾固精凉血方联合西药治疗早期糖尿病肾病疗效显著,值得推广。
[Objective] To observe the effect of nourishing kidney and essence and cool blood prescription combined with Western medicine on early diabetic nephropathy. [Methods] Using randomized parallel control method, 84 inpatients were randomly divided into two groups according to the method of throwing coin. Control group 42 cases of Western medicine treatment. The treatment group, 42 cases of nourishing kidney essence and cooling blood side (mulberry Son of Heaven, Epimedium 12g, medlar, Ligustrum lucidum, raspberry, Eclipta, white peony root of the 15g, cooked Shouwu, Dodder, ), 1 / d, decoction 1000mL, taken sooner or later twice. Western medicine treatment with the control group. Continuous treatment of 60d for a course of treatment. Clinical symptoms, biochemical indicators (blood glucose, postprandial blood glucose 2h, glycosylated hemoglobin, serum creatinine, urinary protein excretion rate), adverse reactions were observed. Continuous treatment of a course of treatment to determine the efficacy. [Result] The treatment group was markedly effective in 17 cases, effective in 19 cases, ineffective in 6 cases, the total effective rate was 85.70%. Control group markedly effective in 10 cases, effective in 16 cases, ineffective in 16 cases, the total effective rate was 61.90%. The treatment group was better than the control group (P <0.05). Blood glucose, 2h postprandial blood glucose, glycosylated hemoglobin, serum creatinine, urinary protein excretion rate were improved in both groups (P <0.05), and the treatment group improved better than the control group (P <0.05). [Conclusion] Zishen Gui Jing Liang Xue Fang combined with western medicine has significant curative effect on early diabetic nephropathy and is worth popularizing.