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目的对慢性肾脏病患者行体外循环心脏手术效果的影响进行分析。方法 1046例患者择期接受体外循环心脏手术,根据患者术前肾小球滤过率情况,分为慢性肾脏病组(67例)与非慢性肾脏病组(979例),对两组患者临床资料进行回顾性分析并分析治疗情况。结果慢性肾脏病组发病率为6.4%;两组患者年龄,左室射血分数,性别,合并高血压、高脂血症、心功能不全、糖尿病、心肌梗死病史及脑血管病史所占比例差异均具有统计学意义(P<0.05);慢性肾脏病组体外循环时间、主动脉阻断时间、机械通气时间、ICU时间与住院时间长于非慢性肾脏病组(P<0.05),术中输血率、术后并发症发生率与死亡率高于非慢性肾脏病组(P<0.05)。结论慢性肾脏病患者行体外循环心脏手术具有较高风险,术后并发症发生率及患者死亡率较高。
Objective To analyze the effect of cardiopulmonary bypass on patients with chronic kidney disease. Methods 1046 patients undergoing cardiopulmonary bypass were enrolled in this study. According to the preoperative glomerular filtration rate, patients were divided into chronic kidney disease group (67 cases) and non-chronic kidney disease group (979 cases). The clinical data Retrospective analysis and analysis of treatment. Results The incidence of chronic kidney disease was 6.4%. The differences of age, left ventricular ejection fraction, gender, hypertension, hyperlipidemia, heart failure, diabetes mellitus, myocardial infarction and the history of cerebrovascular disease (P <0.05). The extracorporeal circulation time, aortic cross-clamping time, mechanical ventilation time, ICU time and hospital stay in chronic kidney disease group were longer than those in non-chronic kidney disease group (P <0.05) , Postoperative complications and mortality were higher than those in non-chronic kidney disease group (P <0.05). Conclusion Patients with chronic kidney disease undergoing cardiopulmonary bypass have a higher risk of postoperative complications and higher mortality.