干燥综合征临床上并不少见,但干燥综合征引起肾小管性酸中毒周期性麻痹报道较少。今将我院收治的一例报告如下:患者,女、47岁,蒙族,干部,住院号130661,患者从1977年发现口眼、皮肤干燥,无汗。因口干影响咀嚼、吞咽、讲话,不能进干硬食物。自觉无泪或泪液极少、口渴、多尿、夜尿多和持续性蛋白尿(但无浮肿、高血压)、乏力、纳差而二絮(麝香草酚絮状和浊度试验)不正常,且反复关节肌肉酸痛,血沉快(但无关节畸形和 X 线骨与关节改变)。故多年来一直被误诊为“肾炎”、“肝炎”、“风湿性关节炎”等疾病。近四年乏力、纳差、口眼干加重,持续性多尿,每日尿量经常在2500毫升以上(但肾功能正常), Sjogren’s syndrome is not uncommon in clinical practice, but Sjogren’s syndrome causes fewer reports of periodic paralysis of renal tubular acidosis. A case report from our hospital is as follows: Patient, Female, 47 years old, Mongolian, Cadre, Hospitalization No. 130661, Patient Obstructing the mouth from 1977, dry skin, no sweat. Due to dry mouth affect chewing, swallowing, speech, can not enter the hard and dry food. No tears or tear rarely, thirst, polyuria, nocturia and persistent proteinuria (but no edema, high blood pressure), fatigue, anorexia and two Xu (thymol flocculent and turbidity test) Normal, and repeated joint soreness, rapid ESR (but no joint deformity and X-ray and joint changes). For years, it has been misdiagnosed as “nephritis”, “hepatitis”, “rheumatoid arthritis” and other diseases. Nearly four years of fatigue, anorexia, dry mouth exacerbation, persistent polyuria, daily urine output is often more than 2500 ml (but normal renal function),