论文部分内容阅读
(本刊讯)中科院大连化学物理研究所在铁催化[2+2+2]环加成反应合成吡啶化合物的研究中取得新进展,相关结果以通讯的形式发表在最近一期的《德国应用化学》上(Angew.Chem.Int.Ed.2011,50,7162-7166)。吡啶及其衍生物被广泛用作有机合成试剂或作为医药、农药的生产中间体。环加成反应构建吡啶化合物原子利用率高达100%,是构建吡啶单元最直接、最高效的方法。尽管科学界在这一领域里付出了长期的努力并开发出了诸如Co、Rh、Ru、Ni、Ti等金属催化体系,但从1876年至今,该领域
(Ben Kanxun) Dalian Institute of Chemical Physics, Chinese Academy of Sciences made new progress in the study of [2 + 2 + 2] cycloaddition reaction of pyridine compounds. Relevant results were published in the recent issue of “German Applications Chem. ”(Angew. Chem. Int. Ed. 2011, 50, 7162-7166). Pyridine and its derivatives are widely used as organic synthesis reagents or as pharmaceutical, pesticide production intermediates. The cycloaddition reaction of pyridine compounds with up to 100% atomic utilization is the most direct and efficient method for constructing pyridine units. Although the scientific community has made long-term efforts in this field and has developed metal-catalyzed systems such as Co, Rh, Ru, Ni, Ti and so on, from 1876 to the present, the field