目的:探讨在低温等离子灭菌时，无纺布与特卫强两种包装材料的不同装载方式对过氧化氢吸附程度及注射期压力的影响。方法:2019年4—6月，在郑州大学第一附属医院消毒供应中心，将6个空硅树脂器械盒分为2种包装方式，3个采用100 cmn 2的无纺布双层包装，3个采用60 cm× 20 cm的特卫强纸塑袋单层包装。对照组将无纺布包装的3个待灭菌包放在灭菌器上层架，特卫强包装的3个待灭菌包放在下层架；实验组装载顺序相反，特卫强包装的3个待灭菌包放在上层架，无纺布包装放在下层架。两种方式装载量均为70%，按正规流程分别进行20锅次灭菌。灭菌结束后立即检测无菌包吸附过氧化氢浓度，并记录各锅次注射期压力。n 结果:实验组无纺布、特卫强包装的无菌包过氧化氢吸附浓度分别为（11.120±4.187）、（8.205±4.181）ppm，差异有统计学意义（n t=2.203，n P<0.05）；对照组两种包装材质过氧化氢吸附浓度分别为（13.745±3.754）、（8.065±4.599）ppm，差异有统计学意义（n t=4.279，n P<0.01）；两组间无纺布的吸附浓度比较差异有统计学意义（n t=2.088，n P0.05）。实验组注射阶段压力为（9.410±0.188）Torr，对照组为（9.121±0.243）Torr，差异有统计学意义（n t=4.215，n P<0.01）。n 结论:实施过氧化氢低温等离子灭菌时，特卫强包装对过氧化氢的吸附性弱，更宜在灭菌时使用；混合装载时，将特卫强、无纺布包装的待灭菌包分别放在上层和下层，可减少包装材料对过氧化氢吸附量，提高灭菌时注射期压力，使灭菌质量更有保障。“,”Objective:To explore effects of different loading modes of non-woven fabric and Tyvek packaging materials on degree of hydrogen peroxide adsorption and pressure during injection during low temperature plasma sterilization.Methods:From April to June 2019, 6 empty silicone resin instrument boxes were divided into two packaging methods in Disinfectant Supply Center of the First Affiliated Hospital of Zhengzhou University, 3 of which were double-packed with 100 cmn 2 non-woven fabric and 3 of which were single-packed with 60 cm×20 cm Tvek paper-plastic bags. In the control group, the 3 non-woven packages to be sterilized were placed on the upper shelf of the sterilizer, and the 3 Tyvek packages to be sterilized were placed on the lower shelf. The loading order of the experimental group was reversed. The three packages of Tyvek packaging to be sterilized were placed on the upper shelf, and the three packages of non-woven packaging were placed on the lower shelf. The loading capacity of the two methods was 70%, and 20 times of sterilization were respectively carried out according to the normal process. The concentration of hydrogen peroxide adsorbed by the sterile bags was detected immediately after sterilization, and the pressure during each injection period was recorded.n Results:The adsorption concentrations of hydrogen peroxide in sterile packages of non-woven fabric and Tevek in the experimental group were respectively (11.120±4.187) ppm and (8.205±4.181) ppm, and the difference was statistically significant (n t=2.203, n P<0.05) . The adsorption concentrations of hydrogen peroxide of the two packaging materials in the control group were respectively (13.745±3.754) ppm and (8.065±4.599) ppm, and the difference was statistically significant (n t=4.279, n P<0.01) . The difference in the adsorption concentration of non-woven fabrics between the two groups was statistically significant (n t=2.088, n P0.05) . The pressure during injection of the experimental group was (9.410±0.188) Torr, and that of the control group was (9.121±0.243) Torr, and the difference was statistically significant (n t=4.215, n P<0.01) .n Conclusions:When low temperature plasma sterilization of hydrogen peroxide is carried out, Tyvek packaging has adsorption of weak hydrogen peroxide, so it is more suitable for sterilization. In the mixed loading, the sterilization packages packed with Tyvek and non-woven fabric are respectively placed on the upper and lower layers, which can reduce the adsorption amount of hydrogen peroxide of packaging materials, improve the pressure during the injection period of sterilization and ensure the sterilization quality.