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研究以乙醇乙酯为主要溶媒的复方中药烧伤喷雾剂的安全性和药效学。豚鼠皮肤急性毒性试验、皮肤刺激试验、皮肤过敏试验及烧伤实验表明,复方烧伤喷雾剂对金黄色葡萄球菌、绿脓假单胞菌、大肠埃希氏菌、普通变形杆菌都有一定的抑菌作用,对豚鼠Ⅲ°烧伤的抗感染作用非常显著,可明显促进烧伤创面的愈合。
To study the safety and pharmacodynamics of compound Chinese herbal burn sprays with ethyl alcohol as the main solvent. Guinea pig skin acute toxicity test, skin irritation test, skin allergy test and burn test showed that the compound burn spray has a certain antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Proteus vulgaris Role, on guinea pig Ⅲ ° burns anti-infective effect is very significant, can significantly promote the healing of burn wounds.