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目的探讨重组人生长激素（r－hGH）对严重烧伤合并全身炎症反应综合症（SIRS）或脓毒症的疗效和作用环节。方法52例严重烧伤患者，根据应用或未应用r－hGH分成应用组和非应用组，比较二组患者的体温、前白蛋白（PALB）、呼吸机应用时间（VENTD）、创面愈合情况、ICU病房治疗时间（SICUD）及其生存率等与治疗有关的因素。结果二组患者伤后并发症发生无显著差异。但从其并发症的治疗结果看，r－hGH治疗组患者的WBC异常时间、平均PALB值及异常时间、胃肠营养不耐受时间、成人呼吸窘迫综合征（ARDS）救治结果及其供皮区创面和单次植皮愈合时间、SICU时间显著较短，生存率明显增高。结论r－hGH对烧伤后并发SIRS和脓毒症有显著治疗作用。
Objective To investigate the therapeutic effect and effect of recombinant human growth hormone (r-hGH) on severe burns with systemic inflammatory response syndrome (SIRS) or sepsis. Methods Fifty-two patients with severe burn were divided into application group and non-application group with or without r-hGH. The body temperature, Pre-albumin (PALB), VENTD, wound healing, ICU Ward treatment time (SICUD) and its survival rate and other treatment-related factors. Results There was no significant difference in the postoperative complications between the two groups. However, the results of the treatment of complications, r-hGH treatment group patients with abnormal WBC time, mean PALB value and abnormal time, gastrointestinal intolerance time, adult respiratory distress syndrome (ARDS) treatment results and the donor skin District wounds and single skin graft healing time, SICU significantly shorter duration, significantly higher survival rate. Conclusion r-hGH has a significant therapeutic effect on SIRS and sepsis after burn.