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用单向免疫扩散法测定了36例冠心病(心绞痛14例、急性心肌梗塞22例)病人血清α_1-抗胰蛋白酶(α_1-AT)。结果显示,冠心病病人的血清α_1-AT 含量明显低于正常人(P<0.001);心绞痛与急性心肌梗塞间无差异(P>0.05)。表明冠心病病人存在着低α_1-AT 血症。
The serum level of α 1-antitrypsin (α 1 -AT) in 36 patients with coronary heart disease (14 with angina pectoris and 22 with acute myocardial infarction) was determined by one-way immunodiffusion. The results showed that the serum level of α_1-AT in patients with coronary heart disease was significantly lower than that in normal people (P <0.001). There was no difference between angina pectoris and acute myocardial infarction (P> 0.05). Show that patients with coronary heart disease have low α_1-AT hyperlipidemia.