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对126例中国农村高血压合并左心室肥厚(HT-LVH)患者追踪观察10年,并以年龄、性别、职业和地区相匹配的163例单纯高血压(HT)与275例正常人做为非暴露组,进行队列研究。结果发现我国农村HT-LVH患者死亡原因虽以脑卒中居多,但矫正血压因素后,LVH本身并非脑卒中独立危险因子,然仍为心血管意外的独立危险因子。LVH所以合并脑卒中较多,是由于其血压均值在3组中最高的缘故。矫正血压因素后,心电图单纯左心室高电压的脑卒中与心血管意外危险因素都消失,只有左心室肥厚加劳损才是心血管意外的独立危险因素。建议不必把左心室高电压列为心、脑血管意外的危险因子。在低水平范围内,血胆固醇的高低对脑卒中意外发生率无影响。
A total of 126 Chinese patients with hypertensive patients with left ventricular hypertrophy (HT-LVH) underwent 10 years of follow-up and were analyzed by age, sex, occupation, and region of 163 hypertensive patients (HT) and 275 normal subjects Exposed to cohort study. The results showed that the cause of death in rural HT-LVH patients in our country was mostly stroke. However, LVH itself was not an independent risk factor for stroke after correction of blood pressure, and was still an independent risk factor for cardiovascular accidents. LVH so more stroke, because of its mean blood pressure in the three groups the highest reason. Correction of blood pressure, ECG simple left ventricular high voltage stroke and cardiovascular risk factors have disappeared, only the left ventricular hypertrophy and fatigue is an independent risk factor for cardiovascular accidents. It is recommended not to list the left ventricular high voltage as a risk factor for heart and cerebrovascular accidents. In the low range, the level of blood cholesterol has no effect on the accidental stroke rate.