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按病例对照研究设计在克山县大骨节病病区和非病区,经右手X线片选3岁～13岁病例205人、第1对照例204人,第2对照例208人,对水、粮、发中硒、锌含量与大骨节病关系进行了病例对照调查,水、粮中硒、锌含量在病例和对照间未见有意义的联系;病例组儿童发中硒,锌含量显著低于两个对照组,但3组几童都处于低硒、低锌营养状态,发中硒部低于0.200ppm,发中锌都低于0.120ppm。所见差别与家庭的经济收入、生活水平、饮食习惯等生活条件有关,这些因素不决定大骨节病的地方性,因此不可能是致大骨节病的最危险因素。
According to the case-control study design Kashin-Beck disease in Keshan County and non-ward, right-X-ray screening of 205 patients aged 3 to 13 years old, the first control 204 cases, the second control 208 cases of water , The content of selenium and zinc in the diet and hair follicles were investigated by case-control. There was no significant correlation between the content of selenium and zinc in water and food between the cases and the control group. The content of selenium and zinc in the cases group was significant Lower than the two control groups, but the three groups of children are in a low selenium, low zinc nutritional status, hair selenium less than 0.200ppm, send zinc are less than 0.120ppm. The difference between the family income and living conditions, eating habits and other living conditions, these factors do not determine the local Kashin-Beck disease, it can not be caused by Kashin-Beck disease the most dangerous factor.