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我们用OKT单克隆抗体(McAb)检测肾移植受者外周血T细胞亚群,并对16例尸体肾移植受者进行分析,其中8例进行手术后(用CsA前),用CsA及时发生排斥(治疗前)时检测比较。另8例较典型病例则分析其排斥反应出现与否以及与T细胞亚群的变化。结果显示OKT检测和临床判断基本相符,提示OKT检测为研究和诊断肾移植受者的急性排斥提供了较好的手段,现报道如下。
We used OKT monoclonal antibody (McAb) detection of renal transplant recipients of peripheral T cell subsets, and 16 cases of cadaver kidney transplant recipients were analyzed, of which 8 cases after surgery (with CsA before), with CsA timely rejection (Before treatment) test comparison. The other 8 cases were more typical cases were analyzed whether the occurrence of rejection and T cell subsets and changes. OKT test results and clinical judgment of the basic line, suggesting OKT test for the study and diagnosis of renal transplant recipients of acute rejection provides a better means are reported below.