近来,NO和cGMP被认为介导了中波紫外线在皮肤中诱导的红斑形成,本研究探讨其在人体黑素细胞的黑素生成过程中的作用。目前,关于培养黑素细胞中黑素生成的调节因素已有很多报道,但其分子机理尚未明了(有报道认为与环磷酸腺苷和蛋白激酶C有关)。NO这种自由基气体是细胞内和细胞间 Recently, NO and cGMP are thought to mediate erythema induced by ultraviolet B radiation in the skin. This study explored the role of NO and cGMP in the melanogenesis of human melanocytes. At present, there are many reports on the regulatory factors of melanogenesis in melanocytes, but the molecular mechanism is not yet clear (it is reported that CAMP and protein kinase C are involved). NO This free radical gas is intracellular and intercellular