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目的:系统评价抗阻力运动强度在衰弱老年人中的剂量-效应关系。方法:全面检索PubMed、Embase、The Cochrane Library、Web of Science、中国知网（CNKI）、万方数据库中关于衰弱老年人抗阻力运动剂量-效应关系的随机对照试验。筛选出符合条件的文献，在提取资料与进行文献质量评价后，使用RevMan 5.3软件进行Meta分析。结果:本次研究共纳入10篇符合条件的随机对照试验，研究对象为454例衰弱期及衰弱前期老年人。经Meta分析，抗阻力运动的训练强度与衰弱老年人的肌肉力量、肌肉耐力、身体功能之间存在剂量-效应关系。无论是低强度还是高强度抗阻力运动，均可以显著增加衰弱老年人的腿部肌肉力量（n MD=4.58，95%n CI 3.34~5.82，n P<0.05）和肌肉耐力（n MD=12.27，95%n CI 6.54~17.99，n P<0.05）。而高强度抗阻力运动相比低强度抗阻力运动，增加衰弱老年人的腿部肌肉力量（n MD=7.97，95%n CI 0.85~15.09，n P<0.05）和肌肉耐力（n MD=6.94，95%n CI 5.21~8.66，n P<0.05）的优势更明显。综合椅子坐立试验和爬楼梯测试的结果分析发现，低强度抗阻力运动对衰弱老年人的身体功能改善并无明显优势，而高强度抗阻力运动则可以显著改善衰弱老年人的身体功能（n MD=-5.8，95%n CI -7.31~-4.29，n P<0.05；n MD=-1.20，95%n CI -2.17~-0.23，n P<0.05）。n 结论:抗阻力运动可以显著改善衰弱老年人的肌肉力量、肌肉耐力及身体功能，高强度抗阻力运动比低强度抗阻力运动效果更明显。“,”Objective:To systematically evaluate the dose-response relationships of resistance exercise intensity in frail elderly.Methods:A comprehensive search of randomized controlled trials on the dose-response relationships of resistance exercise for frail elderly in PubMed, Embase, The Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), and Wanfang Database. The documents that met the conditions were screened out, and after the data were extracted and the quality of the documents were evaluated, the RevMan 5.3 software was used for Meta analysis.Results:A total of 10 eligible randomized controlled trials were included in this study. The subjects of the study were 454 cases of frail and pre-frail elderly. After Meta analysis, there was a dose-response relationships between the training intensity of resistance exercise and the muscle strength, muscle endurance, and physical function of frail elderly. Both low-intensity and high-intensity resistance exercises can significantly increase the leg muscle strength of frail elderly people (n MD=4.58, 95%n CI 3.34-5.82, n P<0.05) and muscle endurance (n MD=12.27, 95%n CI 6.54-17.99, n P<0.05). Compared with low-intensity resistance exercise, high-intensity resistance exercise increased leg muscle strength of frail elderly people (n MD=7.97, 95%n CI 0.85-15.09, n P<0.05) and muscle endurance (n MD=6.94, 95%n CI 5.21-8.66, n P<0.05) showed more obvious advantages. The analysis of the results of the chair sitting test and the stairs climbing test shows that low-intensity resistance exercise has no obvious advantage in improving the physical function of frail elderly people, while high-intensity resistance exercise can significantly improve the physical function of frail elderly people (n MD=-5.8, 95%n CI -7.3--4.29, n P<0.05;n MD=-1.20, 95%n CI-2.17--0.23,n P<0.05).n Conclusions:Resistance exercise can significantly improve the muscle strength, muscle endurance and physical function of the frail elderly. High-intensity resistance exercise is more effective than low-intensity resistance exercise.