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目的:加深对传染性单核细胞增多症(infectious mononucleosis,IM)的认识,以提高对肝功能损害及心肌损害的早期发现率,便于及早治疗。方法:回顾性分析58例IM患儿的临床资料。结果:58例IM患儿中伴肝功能损害30例(52%),伴心肌损害96%(43/45),其中14例行心电图检查,正常6例(43%),异常8例(57%)。经更昔洛韦、利巴韦林、强的松等治疗,并给予护肝、营养心肌等,治愈37例(64%),好转19例(33%),自动出院2例(3%)。结论:IM患儿肝功能损害及心肌损害的发生率较高,提示对IM患儿应及时行肝功能、心肌酶谱及心电图检查,以便早期发现,及时治疗。
Objective: To deepen the understanding of infectious mononucleosis (IM) to improve the early detection of liver damage and myocardial damage, and to facilitate early treatment. Methods: A retrospective analysis of 58 cases of IM clinical data. Results: Fifty-eight cases (52%) had liver dysfunction and 96% (43/45) had myocardial damage, of which 14 had electrocardiogram, 6 cases were normal, and 8 cases were abnormal %). 37 cases (64%) were cured, 19 cases (33%) were cured, 2 cases were discharged automatically (3%), the others were treated with ganciclovir, ribavirin and prednisolone, . Conclusion: The incidence of liver dysfunction and myocardial damage in children with IM is high, suggesting that liver function, myocardial enzymes and electrocardiogram should be timely detected in children with IM for early detection and prompt treatment.