在以往的报道中 ,人们已对胰导管癌 (PDAC)和吸烟的关系进行了研究 ,尽管其结论尚不一致 ,但可以肯定 PDAC及一些癌前病变的发生率在大量吸烟人群中比不吸烟的增高 2～ 3倍。其分子学方面 ,主要表现为 K- ras原癌基因激活。本实验从另一角度 ,对非肿瘤性胰腺疾病中 K- ras突变 In previous reports, the relationship between pancreatic ductal carcinoma (PDAC) and smoking has been studied and although the conclusions are not consistent, it is certain that the incidence of PDAC and some precancerous lesions is higher in non-smokers than in non-smokers Increase 2 to 3 times. The molecular, mainly as K-ras protooncogene activation. This experiment from another perspective, non-neoplastic pancreatic disease K-ras mutation