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目的研究2型糖尿病血清癌胚抗原(CEA)水平变化及临床意义。方法选取2009-09-2009-12我院内分泌科2型糖尿病住院患者110例,同时期肿瘤科住院90例及健康体检者70例,采用电化学发光法测定血清CEA水平。结果健康对照组CEA为(2.09±0.77)ng/ml,糖尿病患者组CEA中位数3.69 ng/ml,肿瘤患者组CEA中位数13.07ng/ml。三组之间两两比较差异均有统计学意义(P<0.017)。结论糖尿病CEA水平高于健康人群,而肿瘤患者CEA水平又明显高于糖尿病患者。糖尿病人群应定期监测CEA水平,早期发现有无合并肿瘤。
Objective To study the changes and clinical significance of serum carcinoembryonic antigen (CEA) in type 2 diabetic patients. Methods A total of 110 inpatients with type 2 diabetes mellitus in Department of Endocrinology of our hospital from September 2009 to September 2009 were enrolled in this study. 90 inpatients with oncology and 70 healthy people were enrolled in this study. Serum CEA level was determined by electrochemiluminescence. Results The CEA of healthy controls was (2.09 ± 0.77) ng / ml, the median CEA of diabetic patients was 3.69 ng / ml, and the median of CEA was 13.07 ng / ml of cancer patients. The differences between the three groups were statistically significant (P <0.017). Conclusion The level of CEA in diabetes is higher than that in healthy people, while the level of CEA in cancer patients is obviously higher than that in diabetic patients. Diabetes patients should regularly monitor the level of CEA, early detection of tumor with or without consolidation.