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本文采用高效液相色谱法检测了１１例闭塞性脑血管病患者及２２例对照者的脑脊液中多胺（腐胺、精胺及亚精胺）的含量。结果表明：精胺、亚精胺改变不大，但腐胺在病人组的脑脊液中含量明显高于对照组。病人组腐胺升高与梗塞灶多少无关，但与梗塞发生的部位有关：病灶位于基底节区者明显高于位于脑其他部位者。腐胺升高主要发生在病后４－６天。本文对上述结果进行了初步探讨，认为腐胺的升高与脑缺血后再灌流期脑损害相关。
In this paper, the contents of polyamines (putrescine, spermine and spermidine) in cerebrospinal fluid in 11 patients with occlusive cerebrovascular disease and 22 controls were detected by high performance liquid chromatography. The results showed that: spermine, spermidine little change, but putrescine in patients with cerebrospinal fluid was significantly higher than the control group. Patients with elevated putrescine and infarct size has nothing to do, but with the infarction of the site: lesions in the basal ganglia were significantly higher than in other parts of the brain. Putrescine increases mainly in the 4-6 days after the disease. In this paper, a preliminary study of the above results, that elevated putrescine and cerebral ischemia after reperfusion related brain damage.