我们应用国产乙型肝炎血源疫苗(下称HB疫苗)对初免者在观察免疫持久性的基础上,于第5年进行了加强接种。现将结果报告如下。1 对象与方法1.1 对象年龄在13～15岁,经3剂HB疫苗初免(0、1、2)5年后的烟台市区学生70人。1.2 疫苗用卫生部长春生物制品研究所生产的HB 疫苗,批号8908-20,其HBsAg 含量为10μg/ml。1.3 接种取HB 疫苗,对上述对象于初免后第60个月加强接种1次,部位为前臂三角 We use domestic hepatitis B blood vaccine (hereinafter referred to as HB vaccine) for the first immunization in observing the immune persistence, based on the fifth year of intensive vaccination. The results reported below. 1 Subjects and Methods 1.1 Subjects aged 13 to 15 years old, three doses of HB vaccine initial (0, 1, 2) after 5 years in Yantai city 70 students. 1.2 Vaccine With the Ministry of Health Changchun Institute of Biological Products produced HB vaccine, batch number 8908-20, the HBsAg content of 10μg / ml. 1.3 vaccination take HB vaccine, the above object in the first 60 months after the first vaccination to strengthen the vaccination 1, part of the forearm triangle