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目的：探讨维生素Ｂ１ 、Ｂ２ 、Ｃ 及烟酸对机体的热保护作用及其可能的机理。方法：以果蝇为热暴露动物模型，以３６ ．５ ℃为热暴露温度，观察上述四种维生素的不同剂量干预下的果蝇的平均生存时间及热应激蛋白含量的变化。结果：除烟酸外，其余维生素均有一种或几种干预的剂量能显著增加果蝇的热生存时间及ＨＳＰ７０ 含量。结论：维生素Ｂ１ 、Ｂ２ 、Ｃ能显著增加果蝇生存时间，在有效剂量干预下果蝇的ＨＳＰ７０ 含量也增加，提示它们对果蝇具有热保护作用，并且这种保护作用的机制可能是通过增加ＨＳＰ的含量来实现的
Objective: To investigate the protective effect of vitamin B1, B2, C and nicotinic acid on the body and its possible mechanism. Methods: Drosophila heat exposed animal models to 36. 5 ℃ for the heat exposure temperature, observed the above four vitamins at different doses of Drosophila average survival time and heat stress protein content changes. Results: In addition to nicotinic acid, all the other vitamins had one or more intervention doses that significantly increased the heat-survival time and HSP70 content of fruit flies. CONCLUSION: Vitamin B1, B2 and C can significantly increase the survival time of Drosophila melanogaster, and the content of HSP70 in Drosophila melanogaster increased with the effective dosage, suggesting that they have a thermal protective effect on Drosophila melanogaster, and the mechanism of this protective effect may be increased by increasing HSP content to achieve