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在连续应用硝酸酯期间血液动力学及临床效应减弱，其机理可能与反向调节性交感神经活性增加及肾素一血管紧张素一醛固酮系统激活有关。本文研究了卡托普利是否能够增强硝酸甘油（NTG）对动静脉的即时扩血管效应及防止对NTG耐受性形成。选择26例左心功能正常的冠心病患者作为研
The hemodynamic and clinical effects weakened during the continuous application of nitrates, which may be related to increased upregulation of sympathetic nerve activity and activation of the renin-angiotensin-aldosterone system. This article investigates whether captopril can enhance immediate vasodilator effects of NTG on arteriovenous and prevent NTG tolerance formation. 26 patients with normal left ventricular function in coronary heart disease as research