论文部分内容阅读
本文用ELISA法测定了187次正常人(40例)及各类病人(胰腺癌33例,其它恶性肿瘤61例,消化道良性疾病53例)的血清结肠胰腺癌相关抗原浓度。以正常组均值加上2倍标准差(25.27μg/ml)为正常上限,胰腺癌组该抗原浓度明显升高(57.25±82.93μg/ml,M±S),而其它各组无升高。本法诊断胰腺癌的敏感性和特异性分别为69.70％和96.49％,提示测定血清结肠胰腺癌相关抗原对胰腺癌的诊断有一定价值.
In this study, serum colon pancreatic cancer-associated antigen concentration was determined by ELISA in 187 normal subjects (40 cases) and various types of patients (33 cases of pancreatic cancer, 61 cases of other malignant tumors, and 53 cases of benign diseases of the digestive tract). With the normal group mean plus 2 standard deviations (25.27 μg/ml) as the upper limit of normal, the antigen concentration in the pancreatic cancer group was significantly increased (57.25±82.93 μg/ml, M±S), but not in the other groups. The sensitivity and specificity of this method for the diagnosis of pancreatic cancer were 69.70% and 96.49%, respectively, suggesting that the determination of serum colon pancreatic cancer-associated antigen has a certain value for the diagnosis of pancreatic cancer.