垂体腺瘤是生长在鞍内的常见肿瘤,近年来由于CT,显微器械的进一步革新对微腺瘤的早期诊断及手术的全切有了新的进展。现就我院经病理证实的140例垂体腺瘤报告如下: 临床资料一、一般资料:本组男68例,女72例,平均年龄37岁。病程1年～20年,平均4年6个月。肿瘤最大直径50mm,最小直径10mm以下。二、症状和体征:头痛81例,视力下降121例,视野损害103例,眼底乳头原发萎缩100例,肢端肥大54例,闭经50例,溢乳21例,性功能减退45例,肥胖62例,毛发脱落45例,多饮多尿10例。三、内分泌检查:内分泌检查除糖耐量103例ACTH46例外均为30例,其中T_3低下8例,T_4低下7例,生长激素增高8例,泌乳素增高20例,甲功低下10例,17-羟增高5例,17-酮增高4例,糖耐量增高61例,ACTH增高19例。四、放射学检查:蝶鞍扩大,鞍背破坏124例,属于侵蚀型Ⅲ级局限型。局限型Ⅰ～Ⅱ级10 Pituitary adenoma is a common tumor that grows in the saddle. In recent years, due to the further innovation of CT and micro-instrumentation, new advances have been made in the early diagnosis of microadenomas and the complete surgical resection. Now 140 cases of pituitary adenoma confirmed by pathology in our hospital are reported as follows: Clinical data First, general information: This group of 68 males and 72 females, the average age of 37 years. Duration of 1 year to 20 years, an average of 4 years and 6 months. The maximum diameter of the tumor is 50mm and the minimum diameter is 10mm or less. II. Symptoms and signs: 81 cases of headache, 121 cases of vision loss, 103 cases of visual field damage, 100 cases of primary atrophy of fundus papilla, 54 cases of acromegaly, 50 cases of amenorrhea, 21 cases of galactorrhea, 45 cases of sexual dysfunction, obesity 62 For example, there were 45 cases of hair loss and 10 cases of polydipsia. Third, endocrine examination: endocrine examination in addition to glucose tolerance of 103 cases of ACTH46 exception were 30 cases, of which T_3 low in 8 cases, T_4 low in 7 cases, growth hormone increased in 8 cases, elevated prolactin in 20 cases, a low power in 10 cases, 17- Hydroxygen increased in 5 cases, 17-ketone increased in 4 cases, glucose tolerance increased in 61 cases, and ACTH increased in 19 cases. Fourth, radiological examination: sella expansion, saddle and back destruction in 124 cases, are classified type III erosion type. Limited Type I to II 10