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研究 E- cd在胃癌、癌旁组织及转移淋巴结中的表达。用免疫组化方法检测 E- cd的表达 ,用图像分析仪进行定量分析。结果显示胃癌及转移淋巴结中 E- cd的表达明显低于癌旁组织 (P<0 .0 0 1)。分化不良胃癌中 E- cd的表达明显低于分化良好胃癌中的表达 (P<0 .0 5 )。结果表明 E- cd可作为判断胃癌预后的指标。
To study the expression of E-cd in gastric cancer, paracancerous tissues and metastatic lymph nodes. The expression of E-cd was detected by immunohistochemistry and quantified by image analyzer. The results showed that the expression of E-cd in gastric cancer and metastatic lymph nodes was significantly lower than that in adjacent non-cancerous tissues (P <0.01). The expression of E-cd in poorly differentiated gastric cancer was significantly lower than that in well-differentiated gastric cancer (P <0.05). The results show that E-cd can be used as an indicator of gastric cancer prognosis.