论文部分内容阅读
子痫前期是孕妇及其胎儿致病与死亡的主要原因,虽然这种疾患的病因和发病机理的关系还不清楚,但一般相信子宫和胎盘的缺血起重要作用。由血管壁合成的前列腺素可能对调节血管张力和血小板血管壁之间的相互影响有帮助,因而调控子宫和胎盘的血流。最近作者曾报告胎儿的血管具有高度合成PGI_2的能力,并认为PGI_2有调节胎儿的循环中起重要作用,本研究证明在重度子痫前期患者中,胎儿的脐带和胎盘血管中PGI_2的产生较正常妊娠明显减少。实验分为3组:第一组是9例无合并症的妇女,平均年龄为17～35岁,其中4例为初产妇,2
Pre-eclampsia is the main cause of maternal and fetal fetal pathology and death. Although the relationship between etiology and pathogenesis of this disease is unclear, it is generally believed that ischemia of uterus and placenta play an important role. Prostaglandins synthesized by the vascular wall may help regulate the interaction between vascular tone and the platelet wall, thereby regulating the blood flow to the uterus and placenta. Recently, the author reported that fetal blood vessels have a high ability to synthesize PGI_2 and that PGI_2 plays an important role in the regulation of fetal circulation. This study demonstrated that PGI_2 production in umbilical cord and placental blood vessels of the fetus is more normal than normal in severe preeclampsia Pregnancy decreased significantly. The experiment was divided into 3 groups: the first group was 9 women without complications, the average age of 17 to 35 years old, 4 cases of primipara, 2