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对24例结节病(4例活动期,20例非活动期)患者进行了67Ga显像,并测定了血清血管紧张素转化酶(SACE),进行了肺功能及CT或X线检查。4例活动期结节病患者中有3例表现为双侧肺门对称性放射性浓聚,似“八”字状;其中2例患者因双侧泪腺和腮腺67Ga摄取增高,呈特殊的“熊猫”面容。4例活动期结节病患者其病灶对67Ga摄取明显增多,相当于3+;20例非活动期患者中8例(40%)67Ga显像异常,相当于1+,表明67Ga在不同活动性肺结节病时其病灶摄取的变化是不同的。在67Ga显像异常的12例患者中,4例活动期SACE明显高于正常,另8例非活动期患者的SACE均在正常范围,表明结节病在临床上没有炎症表现时,SACE、CT不能判断其活动状态,但病灶区持续有67Ga摄取时,则提示结节病仍处于活动状态,常为停用或减用激素的反指征。
Sixty-seven patients with sarcoidosis (4 active, 20 inactive) underwent 67Ga imaging and serum angiotensin converting enzyme (SACE) was measured for pulmonary function and CT or X-ray examination. Three of the four patients with active sarcoidosis showed bilateral hilar-symmetric radioactive buildup, which appeared to be “eight” in shape. Two of the patients had increased uptake of 67Ga in the bilateral lacrimal and parotid glands, "face. In 4 patients with active sarcoidosis, 67Ga uptake was significantly increased in lesions, which corresponded to 3+. Eighty (40%) 67Ga imaging abnormalities in 20 inactive patients corresponded to 1+, indicating that 67Ga was expressed in different active pulmonary tuberculosis Changes in the incidence of disease when the disease is different. In 67Ga imaging abnormalities in 12 patients, 4 cases of active SACE was significantly higher than the normal, and the other 8 cases of inactive patients with SACE were in the normal range, indicating no clinical manifestations of sarcoidosis, SACE, CT Can not determine the activity status, but the lesions continue to have 67Ga uptake, suggesting that sarcoidosis is still active, often disable or reduce the use of anti-anti-indications of hormones.