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目的:探讨TACE联合CT引导RFA治疗肝癌的疗效。方法:回顾性分析经确诊为HCC的73例临床资料,按照介入手段不同分为TACE组(n=38)和TACE+RFA组(n=35),比较两组治疗效果、生存率及预后。结果:TACE组肿瘤完全坏死率、术后6个月复发率、术后6个月、1、2年生存率分别为21.05%、44.74%、97.37%、67.57%、44.00%;而联合治疗组分别为82.86%、11.43%、100.00%、88.57%、70.97%。两组比较,肿瘤完全坏死率、术后6个月复发率、术后1、2年生存率均有统计学差异(P=0.000、0.002、0.032、0.041),术后6个月生存率两组间无统计学差异(P=0.337)。结论:TACE联合CT引导RFA治疗肝癌疗效明显优于单纯TACE。
Objective: To investigate the curative effect of TACE and CT-guided RFA in the treatment of liver cancer. Methods: The clinical data of 73 cases diagnosed as HCC were retrospectively analyzed. TACE group (n = 38) and TACE + RFA group (n = 35) were divided according to interventional methods. The treatment effect, survival rate and prognosis were compared between the two groups. Results: The complete tumor necrosis rate in TACE group, the recurrence rate at 6 months after operation and the survival rates at 1, 2 and 6 months after operation were 21.05%, 44.74%, 97.37%, 67.57% and 44.00% Respectively 82.86%, 11.43%, 100.00%, 88.57%, 70.97%. The complete tumor necrosis rate, the recurrence rate at 6 months and the postoperative 1 and 2 year survival rates were statistically different between the two groups (P = 0.000,0.002,0.032,0.041). The survival rate at 6 months after operation There was no significant difference between groups (P = 0.337). Conclusion: TACE combined with CT-guided RFA treatment of liver cancer was significantly better than the simple TACE.