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目的 为了探讨类胰高血糖素肽—1(Glucagon—like peptide—1,GLP—1)在大鼠的胃肠道中的分布情况。方法 应用免疫组织化学ABC法,观察了6只Wistor大鼠胃肠道中GLP—1免疫活性细胞分布情况。结果 大鼠胃肠道中GLP—1免疫活性细胞密度最大的是回肠,其次是结肠和直肠。结论 GLP—1免疫活性细胞主要分布在小肠远端。
Objective To investigate the distribution of Glucagon-like peptide-1 (GLP-1) in the gastrointestinal tract of rats. Methods Immunohistochemical ABC method was used to observe the distribution of GLP-1 immunoreactive cells in the gastrointestinal tract of 6 Wistor rats. Results The highest density of GLP-1 immunocompetent cells in the gastrointestinal tract was ileum, followed by colon and rectum. Conclusion GLP-1 immunocompetent cells mainly distribute in the distal part of the small intestine.