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目的:探讨C反应蛋白(CRP)测定在水痘患儿中的变化及临床意义。方法:对82例水痘患儿血浆CRP值与45例正常对照组(无感染)儿童血浆CRP值进行统计比较。结果:水痘患儿中合并细菌感染组CRP值明显高于单纯病毒感染组与正常对照组,CPR水平差异有显著性(P<0.01),单纯病毒感染组与正常对照组CRP值比较,差异无统计学意义(P>0.05)。结论:水痘患儿血浆CRP水平对鉴别是否合并细菌感染、判断病情变化与疗效、从而指导抗生素的正确使用具有一定价值。
Objective: To investigate the changes of C-reactive protein (CRP) in children with chickenpox and its clinical significance. Methods: The plasma CRP levels in 82 children with chicken pox were compared with those in 45 normal controls (without infection). Results: The CRP of bacterial infection in children with chickenpox was significantly higher than that in the simple virus infection group and the normal control group (P <0.01). There was no significant difference in CRP between the virus infection group and the normal control group Statistical significance (P> 0.05). Conclusion: The level of plasma CRP in children with chickenpox has some value in distinguishing bacterial infection, judging the change and curative effect of disease and guiding the correct use of antibiotics.