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目的:观察36例重度烧伤患者中后期输注血浆冷沉淀的临床效果。方法:把37例重度烧伤患者随机分为两组,第1组18例患者正常治疗;另一组19例患者输注血浆冷沉淀,在其输注冷沉淀前后对血常规、出血时间、纤维蛋白原、纤维结合蛋白(Fn)含量进行测定。结果:输注血浆冷沉淀后与输血前相比,出血时间明显缩短;血浆Fn水平输注后明显增高。结论:对重度烧伤患者早期输注血浆冷沉淀可提高患者血浆Fn水平,缩短出血时间,防止凝血异常,加快烧伤组织修复。
Objective: To observe the clinical effect of mid-late infusion of plasma cryoprecipitate in 36 patients with severe burn. Methods: Thirty-seven patients with severe burn were randomly divided into two groups, 18 patients in group 1 received normal treatment. In the other group, 19 patients received infusion of cryoprecipitate before and after infusion of cryoprecipitate. The blood routine, bleeding time, Protein, fibronectin (Fn) content were measured. Results: Compared with those before transfusion, the bleeding time was significantly shortened after transfusion of cryoprecipitate; the level of Fn in plasma was significantly increased after infusion. Conclusion: The early infusion of plasma cryoprecipitate in patients with severe burn can improve the plasma Fn level, shorten the bleeding time, prevent coagulation abnormalities and accelerate the repair of burn tissue.