论文部分内容阅读
砷及其化合物广泛存在于自然界,应用于工业、农业和医药等领域。砷中毒引起皮肤过度角化及多系统、多器官损害,导致皮肤或器官癌变。近年来有关砷对中枢神经系统作用越来越引起人们重视,砷能通过血、脑屏障进入脑组织,影响脑中化学物质稳定性,从而引起人的思维、学习和行为变化〔1-3〕。本研究通过建立亚急性砷中毒动物模型,观察大鼠
Arsenic and its compounds are widely found in nature, used in industrial, agricultural and pharmaceutical fields. Arsenic poisoning causes hyperkeratosis and multiple system damage of the skin leading to canceration of the skin or organs. In recent years, the effect of arsenic on the central nervous system has attracted more and more attention. Arsenic can enter the brain tissue through the blood and brain barrier and affect the stability of chemical substances in the brain, causing changes in people’s thinking, learning and behavior [1-3] . In this study, animal models of subacute arsenism were established and rats were observed