目的通过分析2010-2013年梧州市艾滋病(HIV)母婴传播阻断工作监测资料,了解梧州市HIV母婴传播阻断综合模式实施的成效。方法收集梧州市2010-2013年的婚前保健人群预防HIV母婴传播咨询率和抗体检测率、孕产妇预防HIV母婴传播咨询率和抗体检测率、感染HIV孕产妇抗病毒药物应用率、感染孕产妇所分娩婴儿药物应用率、感染HIV孕产妇所分娩婴儿满18个月龄HIV检测率和确诊阳性率、HIV阳性孕产妇人工终止妊娠率监测资料,利用EXCEL 2003和SPSS 16.0进行分析。结果 2010-2013年梧州市婚前保健人群预防HIV母婴传播咨询率分别为99.73%、100.00%、100.00%和100.00%,不同年份间比较,差异有统计学意义(χ2=440.526 8,P<0.05);HIV抗体检测率分别为98.64%、99.86%、100.00%和100.00%,不同年份间比较,差异有统计学意义(χ2=1 852.401 2,P<0.05);孕产妇预防HIV母婴传播咨询率分别为93.70%、99.71%、99.96%和99.98%,不同年份间比较,差异有统计学意义(χ2=10 399.748 5,P<0.05);孕产妇HIV抗体检测率分别为96.52%、99.59%、99.96%和99.98%,不同年份间比较,差异有统计学意义(χ~2=508 6.239 3,P<0.05);感染HIV孕产妇抗病毒药物应用率分别为65.38%、80.77%、94.12%和90.28%,不同年份间比较,差异有统计学意义(χ2=9.698 1,P<0.05);感染HIV孕产妇所分娩婴儿抗病毒药物应用率分别为61.54%、88.89%、100.00%和100.00%,不同年份间比较,差异有统计学意义(χ2=23.256 5,P<0.05);感染HIV孕产妇所分娩婴儿满18个月龄HIV检测率分别为93.75%、88.00%、89.47%和90.63%,不同年份间比较,差异无统计学意义(χ2=0.383 4,P>0.05);感染HIV孕产妇所分娩婴儿满18个月龄HIV确诊阳性率分别为0、0、0和3.45%;HIV阳性孕产妇人工终止妊娠率分别为10.34%、26.32%、21.95%和46.15%,不同年份间比较,差异有统计学意义(χ2=11.818 7,P<0.05)。结论通过实施梧州市HIV母婴阻断全方位多层次多平台合作模式,婚前保健人群预防HIV母婴传播咨询率和抗体检测率、孕产妇预防HIV母婴传播咨询率和抗体检测率、感染HIV孕产妇抗病毒药物应用率、感染孕产妇所分娩婴儿药物应用率、HIV阳性孕产妇人工终止妊娠率均显著升高,在提高人群预防HIV母婴传播的意识、预防青年及育龄妇女感染HIV、减少HIV母婴传播和减少HIV感染婴儿的出生等方面取得了积极成效。 Objective To analyze the monitoring data of HIV / AIDS mother-to-child transmission in Wuzhou from 2010 to 2013 so as to find out the effectiveness of comprehensive HIV / AIDS transmission blockade in Wuzhou. Methods Prenatal care of HIV prevention and mother-to-child transmission rates and antibody detection rates in Wuzhou were collected from 2010 to 2013 in Wuzhou City. The rates of mother-to-child HIV / AIDS prevention and mother-to-mother transmission counseling and detection of HIV antibodies were also collected. The application rates of infant medicines delivered by mothers, HIV detection rate and confirmed positive rate of infants born to HIV pregnant women over 18 months of age, monitoring data of HIV-positive pregnant women’s termination of pregnancy rate were analyzed by EXCEL 2003 and SPSS 16.0. Results The counseling rates of maternal and child transmission of HIV among premarital health care workers in Wuzhou during 2010-2013 were 99.73%, 100.00%, 100.00% and 100.00%, respectively, with statistical significance (χ2 = 440.5268, P <0.05) ). The detection rates of HIV antibody were 98.64%, 99.86%, 100.00% and 100.00%, respectively. The difference was statistically significant between different years (χ2 = 1 852.401 2, P <0.05) The rates of HIV antibody detection in pregnant women were 96.52% and 99.59%, respectively (χ2 = 10 399.748 5, P <0.05) , 99.96% and 99.98%, respectively. The difference was statistically significant in different years (χ ~ 2 = 508 6.239 3, P <0.05). The rates of HIV infection were 65.38%, 80.77%, 94.12% And 90.28% respectively. There was significant difference between different years (χ2 = 9.698 1, P <0.05). The rates of applying infantile antiviral drugs in HIV pregnant women were 61.54%, 88.89%, 100.00% and 100.00% , The difference was statistically significant in different years (χ2 = 23.256 5, P <0.05). HIV in infants born to HIV pregnant women over 18 months of age Respectively, which were 93.75%, 88.00%, 89.47% and 90.63%, respectively. There was no significant difference between years (χ2 = 0.383 4, P> 0.05). HIV in infants born to HIV pregnant women over 18 months old was positively diagnosed The rates of termination of pregnancy among HIV-positive pregnant women were 10.34%, 26.32%, 21.95% and 46.15%, respectively. There were significant differences among different years (χ2 = 11.8187, P <0.05). Conclusion Through the implementation of multi-level and multi-level multi-platform HIV-AIDS prevention cooperation model in Wuzhou, premarital health care population to prevent mother-to-child transmission of HIV counseling rate and antibody detection rate, maternal HIV mother-to-child transmission counseling rate and antibody detection rate, HIV infection The rate of application of antiviral drugs for pregnant women, the rate of infant drug delivery in infected pregnant women, and the termination of pregnancy rate of HIV-positive pregnant women were significantly increased. In raising population awareness of prevention of mother-to-child transmission of HIV, prevention of HIV infection among young women of childbearing age, Reduce mother-to-child transmission of HIV and reduce the birth of HIV-infected infants.