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应用体外培养细胞方法观察了甘草锌对成纤维细胞分裂增生的作用。结果表明不同浓度的甘草锌使成纤维细胞贴壁生长率、细胞核分裂系数均高于对照组,形态学发生显著变化。提示甘草锌抗溃疡作用同促进成纤维细胞合成纤维和基质有关。
The effect of licorice zinc on fibroblast cell division and hyperplasia was observed using in vitro cultured cells. The results showed that different concentrations of zinc glycyrrhizic can increase the adherent growth rate and nuclear factor of fibroblasts, and the morphological changes were significant. It is suggested that the anti-ulcer effect of licorice zinc is related to the promotion of fibroblast synthetic fibers and matrix.