自从1909年 Karplus 和 Kreidl 发现电刺激麻醉猫的丘脑下部腹侧区可以引起血压升高和心率加快反应以来,丘脑下部与心血管系统的关系引起了人们的注意。以后人们相继在猫、狗等动物的实验中观察到电刺激丘脑下部某些区域可以引起动脉血压升高、各种类型的心律失常及心电图缺血性改变,甚至可以引起心肌细胞坏死等病理变 The relationship of the hypothalamus to the cardiovascular system has drawn much attention since Karplus and Kreidl (1909) found that electrical stimulation of the ventral hypothalamic area of ​​anesthetized cats can cause an increase in blood pressure and an accelerated heart rate response. Later people have been observed in cats, dogs and other animal experiments that electrical stimulation of the hypothalamus in some areas can cause elevated arterial pressure, various types of arrhythmia and ECG ischemic changes, and even cause myocardial necrosis and other pathological changes