在预先埋植第三脑室导管和预置颈外静脉导管的SD大鼠中,脑室内微量注射β-内啡肽抗血清,并与脑室内注射正常兔血清的大鼠对比。看到注射β-内啡肽抗血清后,ACTH和催乳素因限制性应激的释放,分别被抑制了46.1％和71.2％。说明中枢内源性β-内啡肽可能是ACTH和催乳素在某种应激时相伴释放的重要调节因素之一。 In SD rats that were implanted with a third ventricular catheter and a pre-prepared external jugular vein catheter, β-endorphin antiserum was microinjected into the ventricles and compared with rats injected with normal rabbit serum. After the injection of β-endorphin antiserum, ACTH and prolactin were suppressed by 46.1% and 71.2%, respectively, due to the release of restrictive stress. This suggests that central endogenous β-endorphin may be one of the important regulators of ACTH and prolactin release accompanied by some stress.