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青霉素是临床治疗细菌性感染的抗生素,国内生产,疗效较好,价格低,基层医院使用很普遍。由于青霉素对极少数人造成过敏反应的不良后果,影响临床治疗,实际真正发生Ⅰ型过敏反应(速发型)只有正常人的万分之一左右。临床遇到皮试阴性,用青霉素1～2天后突然发生Ⅱ型过敏反应,医务人员抢救不及后果严重,我们基层医院偶也见到,让人不寒而栗。青霉素皮试结果‘阳性’在临床上反映皮试结果的真实价值并指导临床用药还应仔细考究,因与青霉素基本结构化学基因相类似一组抗生素如氨基苄青霉素,羧基苄青霉素,头孢族抗生素都有交叉过敏,合理评价青霉素皮试阳性反应,防止偶发Ⅰ型青霉素过敏反应是医务人员最关切的。
Penicillin is a clinical treatment of bacterial infections of antibiotics, domestic production, better efficacy, low prices, primary hospital use is very common. Due to the adverse effects of penicillin on a very small number of people causing allergic reactions, affecting clinical treatment, the actual type I allergic reaction (rapid onset) is only about one ten thousandth of normal. Clinically encountered skin test negative, with penicillin 1-2 days after a sudden type Ⅱ allergic reactions, medical rescue less serious consequences, we even see the primary hospital, people chilling. Penicillin skin test results ’positive’ in the clinical test results reflect the true value of the skin and guide clinical medication should be carefully studied because of the basic structural chemical genes similar to penicillin antibiotics such as antibiotics such as ampicillin, carbenicillin, cephalosporins antibiotics Have cross-allergy, a reasonable evaluation of penicillin skin test positive reaction to prevent accidental type I penicillin allergy is the most concern of medical staff.