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微颗粒(microparticles,MPs)是指以出芽的方式,在细胞损伤或激活时,从胞浆膜表面脱落的、大小不等的膜性囊泡[1]。近年研究发现MPs具有很多生物学活性,并且在多种细胞生理过程中扮演重要角色,包括细胞间生物活性信号传递、免疫调节、凋亡、稳定等[2]。MPs携带来源细胞的表面标志物,可以反映来源细胞的各种复杂功能、损伤或激活状态[3]。随着对它的认识不断更新,研究越来越多,已经发现其
Microparticles (MPs) are membrane vesicles of varying sizes that come off the surface of the cytoplasmic membrane during the process of cell damage or activation in the form of budding [1]. Recent studies have found that MPs have a lot of biological activity, and play an important role in a variety of cell physiological processes, including the biological activity of cell signal transduction, immune regulation, apoptosis, stability [2]. MPs carry the surface markers of the source cells and can reflect the complex functions, damage or activation of the cells of origin [3]. As the knowledge of it constantly updated, more and more research has been found