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目的探讨儿童过敏性紫癜(HSP)发生肾损害相关因素,为其预防和治疗提供理论依据。方法对62例HSP发生肾损害的患儿和138例HSP患儿的临床资料进行对比研究。结果皮疹反复发作(OR=2.656,95%CI:1.453~3.564);皮疹持续时间(OR=2.456,95%CI:1.563~3.564);血小板(OR=1.563,95%CI:1.783~2.574)是儿童过敏性紫癜发生肾损害的危险因素。结论皮疹反复发作,皮疹持续时间长,血小板升高的HSP患儿容易发生肾脏损害。
Objective To investigate the related factors of renal damage in children with Henoch-Schonlein Purpura (HSP), and provide a theoretical basis for its prevention and treatment. Methods The clinical data of 62 HSP patients with renal damage and 138 HSP children were compared. (OR = 2.456, 95% CI: 1.563 ~ 3.564); platelets (OR = 1.563, 95% CI: 1.783-2.574) were Risk factors for renal damage in children with Henoch - Schonlein purpura. Conclusions Repeated episodes of rashes, prolonged rashes and kidney damage in children with elevated thrombocytopenia.