肝动脉栓塞化疗联合微波凝固治疗原发性肝癌疗效分析

来源 :中国基层医药 | 被引量 : 0次 | 上传用户:annazky
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目的探讨肝动脉化疗栓塞术联合微波凝固治疗原发性肝癌的疗效。方法72例不能手术切除的中晚期肝癌和拒绝手术的早期肝癌患者随机分为A、B两组。A组:经导管肝动脉化疗栓塞组(TACE组),共39例;B组:肝动脉化疗栓塞联合微波凝固治疗组(联合治疗组),共33例。结果TACE组的完全坏死率、初次复发率及1年生存率分别为30.77%、35.90%和58.97%;而联合治疗组分别为90.91%、6.06%和84.85%。两组间完全坏死率、初次复发率及1年生存率差异均有显著意义(其相应P值分别为0.000、0.003、0.006)。结论肝动脉化疗栓塞联合微波凝固治疗效果明显优于单纯化疗栓塞。 Objective To investigate the efficacy of transcatheter arterial chemoembolization combined with microwave coagulation in the treatment of primary liver cancer. Methods 72 patients with unresectable advanced liver cancer and patients with early-stage liver cancer who refused surgery were randomly divided into A and B groups. A group: transcatheter hepatic arterial chemoembolization group (TACE group), a total of 39 cases; B group: hepatic arterial chemoembolization combined with microwave coagulation treatment group (combination therapy group), a total of 33 cases. Results The complete necrosis rate, initial relapse rate and 1-year survival rate of TACE group were 30.77%, 35.90% and 58.97%, respectively. The combined treatment group was 90.91%, 6.06% and 84.85% respectively. The complete necrosis rate, initial relapse rate and 1-year survival rate were significantly different between the two groups (corresponding P values ​​were 0.000, 0.003, 0.006 respectively). Conclusion Hepatic arterial chemoembolization combined with microwave coagulation therapy is superior to chemotherapy alone embolization.
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