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目的探讨血清Th1、Th2及Th17类细胞因子在妊娠期高血压疾病孕妇中的检测价值。方法选取2015年9月-2016年11月该院收治的66例妊娠期高血压疾病孕妇作为观察组,同时选取同时间段的66例健康孕妇作为对照组,检测与比较两组孕妇血清Th1、Th2及Th17类细胞因子水平,并将轻度、中度及重度妊娠期高血压疾病孕妇的检测结果进行比较。结果观察组的血清IL-2水平低于对照组(P<0.05),其他血清Th1、Th2及Th17类细胞因子均高于对照组(P<0.05),且轻度、中度及重度妊娠期高血压疾病孕妇的血清Th1、Th2及Th17类细胞因子也存在统计学差异(P<0.05)。结论血清Th1、Th2及Th17类细胞因子在妊娠期高血压疾病孕妇中的检测价值较高,对于疾病的诊断、治疗及疾病严重程度均有一定的检测意义。
Objective To investigate the value of serum Th1, Th2 and Th17 cytokines in pregnant women with gestational hypertension. Methods 66 pregnant women with gestational hypertension admitted to our hospital from September 2015 to November 2016 were selected as the observation group and 66 healthy pregnant women in the same period were selected as the control group. The levels of serum Th1, Th2 and Th17 cytokines levels, and mild, moderate and severe gestational hypertension pregnancy test results were compared. Results The level of serum IL-2 in the observation group was lower than that in the control group (P <0.05), and the levels of other Th1, Th2 and Th17 cytokines in the observation group were higher than those in the control group (P <0.05), and mild, moderate and severe gestational The levels of Th1, Th2 and Th17 cytokines in pregnant women with hypertension were also significantly different (P <0.05). Conclusion Serum levels of Th1, Th2 and Th17 cytokines in pregnant women with hypertensive disorder complicating pregnancy are of high value in diagnosis, treatment and disease severity.