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他汀类药物通过对3—羟基3—甲基戊二酰辅酶A(HMG—CoA)还原酶的抑制，可降低血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL—C)，升高高密度脂蛋白胆固醇(HDL—C)。斯堪的那维亚(北欧)辛伐他汀生存研究中证实［1］：辛伐他汀能降低冠心病患者总死亡率30%。其后，普伐他汀亦被证明
Statins can reduce the levels of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), and high increase by inhibiting the 3-hydroxy 3-methylglutaryl coenzyme A Density lipoprotein cholesterol (HDL-C). Simvastatin survival studies in Scandinavia (Nordic) confirm [1] that simvastatin can reduce 30% of patients with CHD overall mortality. Since then, pravastatin has also been demonstrated