纯红细胞性再障(PRCA)是一综合征,其特征为严重的正常色素、正常细胞性贫血,网织红细胞减少,骨髓象除幼红细胞缺乏外均正常。急性自限型PRCA常与药物或感染有关,而慢性PRCA则可是一原发病或继发于其它疾病,后者常累及免疫系统,例如胸腺瘤、SLE(系统性红斑狼疮)、重症肌无力、自身免疫性甲状腺机能减退(甲减)或淋巴增殖性疾病。此外,实验室检查常提示患者免疫功能障碍,例如低丙球血症、副蛋白血症、低补体血症、抗核抗 Pure erythrocytic aplastic anemia (PRCA) is a syndrome characterized by severe normal pigment, normal cell anemia, reticulocytopenia, and myeloid abnormalities except for erythroblasts. Acute self-limiting PRCA is often associated with drugs or infections, whereas chronic PRCA can be a primary disease or secondary to other conditions, the latter often involving the immune system such as thymoma, SLE (systemic lupus erythematosus), myasthenia gravis , Autoimmune hypothyroidism (hypothyroidism), or lymphoproliferative disorders. In addition, laboratory tests often prompt patients with immune dysfunction, such as hypoparathyroidism, paraproteinemia, hypocomplementemia, anti-nuclear resistance