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目的：探讨甲状腺腺瘤和腺癌性甲状腺肿一侧甲状腺腺叶切除术后补充甲状腺素的临床意义。方法；将接受一侧甲状腺腺叶切除术的40例甲状腺腺瘤或腺癌性甲状腺肿患者随机分为两组：A组术后口眼甲状腺片，B组术后不服甲状腺片，比较术前及术后3～6个月血清TT3、TT4及TSH值和超声波检查保留侧甲状腺大小。结果：A组手术前后TT3、TT4、TSH值及保留侧甲状腺大小无明显变化，B组术后3～6个月TT3、TT4较术前下降，TSH较术前上升，保留侧甲状腺较术前增大。术后的各项数据两组比较，均有显著性差异。结论：甲状腺腺瘤和腺癌性甲状腺肿一侧腺叶切除术后保留侧甲状腺腺叶有增生，而术后补充甲状腺素可改变这一现象从而预防甲状腺癌的发生。
Objective: To investigate the clinical significance of thyroxine supplementation after thyroidectomy with thyroid adenoma and adenocarcinoma goiter. Methods: Forty patients with thyroid adenoma or adenocarcinoma goiter undergoing unilateral thyroidectomy were randomly divided into two groups: group A was treated with thyroidectomy, and group B was treated with thyroidectomy before surgery. The serum TT3, TT4, and TSH values were measured 3 to 6 months after surgery, and the size of the thyroid gland remained on the side of the ultrasound examination. Results: There was no significant change in TT3, TT4, TSH and thyroid size before and after operation in group A. TT3 and TT4 decreased in 3 to 6 months after operation in group B compared with preoperative and TSH was higher than before surgery. Increase. The postoperative data showed significant differences between the two groups. CONCLUSIONS: Thyroid adenomas and adenocarcinoma goiters have thyroid gland hyperplasia after lobectomy, and postoperative thyroxine supplementation may alter this phenomenon to prevent thyroid cancer.